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The strong para-directing influence of fluorine in Fnedel-Crafts acylation is illustrated by the reaction of fluorotoluenes with acetyl chloride Treatment of 2-fluorotoluene, 3-fluorotoluene, and 2-fluoro-3-methyltoluene with acetyl chloride and aluminum chloride gives, respectively, 91, 82, and 80% substitution para to fluorine [27]... [Pg.414]

See also in sourсe #XX -- [ Pg.417 , Pg.419 ]

See also in sourсe #XX -- [ Pg.417 , Pg.419 ]

See also in sourсe #XX -- [ Pg.417 , Pg.419 ]