Imperatoria Ostruthium

Oxtruthol. 2-Methyl-2-butenoic acid 2-hydroxy-2-methyi-l-[[( 7-oxo- 7H-furo[3,2-g][l]bemopyran-4-yl)oxy -methyljpropyt ester. CjjHyOji mol wt 386.39. C 65.27%, H 5.74%, O 28.98%. From rhizome of Peucedanum ostruthium L. Koch (Imperatoria ostruthium L.), Umbelliferae Herzog, Koch, Arch. Pharm. 247, 553 (1909). Structure Spath,... 

Kaiser, et al. [276] studied another example of inhibition of phosphorylation process by coumarins. In that study, it was shown that imperatorin, a fiiranocoumarin from Imperatoria ostruthium L. and Ammi majus L., inhibited respiration and phosphorylation of isolated mitochondria of the liver in the presence of succinate [276,326]. 

Metabolic activity of DMAPP and IPP sometimes results in prenylation of plant phenolics leading to prenyl ethers, several of which hare been isolated from woody tissues. For example, imperatorin (12), a prenylated coumarin, is present in the roots of Imperatoria ostruthium (228). From African sneezewood Ptaerox-ylon obliquum, prenyletin (13) was obtained along with several other coumarins (125). Another example of a naturally occurring prenyl ether is the isoflavone, maxima-substance C (14) from roots of Tephrosia maxima (229). Several other ex-... 

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