Immune system viral mimicry

Murphy, P. M. (2001). Viral exploitation and subversion of the immune system through chemokine mimicry. Nat. Immunol. 2, 116-122. 

Over the last several years we have started to learn that chemokine mimicry by herpesvirus is common and important for the virus. What has come as a surprise is that herpesvirus encoded chemokines and chemokine receptors have positive effects and are not only used by the virus to block the chemokine system or evade the host immune response. Accordingly it seems inevitable that these pro-inflammatory chemokine elements play imporant roles in viral growth and dissemination in vivo. 

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