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Immobilization matrices with transduction

Polypyrrole has the potential to provide an effective method for reagentless transduction by immobilization of the ssDNA probe within the polymer matrix. Significant differences in the impedance profile of ssDNA and dsDNA have been demonstrated [59]. The differences in the impedance profile are purportedly based on intercalation differences of the polymer with ssDNA compared to dsDNA. The exact mechanism for impedimetric change resulting from conducting polymer films has not been identified, although it is likely linked, much like the impedimetric response of pure DNA, to the change in ion density that accompanies the double strand compared to the... [Pg.181]

See other pages where Immobilization matrices with transduction is mentioned: [Pg.275]    [Pg.275]    [Pg.133]    [Pg.1495]    [Pg.1499]    [Pg.1505]    [Pg.458]    [Pg.462]    [Pg.468]    [Pg.225]    [Pg.124]    [Pg.964]    [Pg.336]    [Pg.135]    [Pg.114]    [Pg.54]    [Pg.155]    [Pg.338]    [Pg.361]    [Pg.1501]    [Pg.464]    [Pg.1376]    [Pg.361]    [Pg.967]    [Pg.309]    [Pg.261]   


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Immobilization matrix

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