Imipramine Trimethoprim/Sulfamethoxazole

Noninterfering acetaminophen, N-acetylprocainamide, amikacin, amitriptyline, clonazepam, cyclosporine, desipramine, diazepam, digoxin, disopyramide, gentamicin, p-hydrox- q>henobarbital, imipramine, Udocaine, methotrexate, netilmicm, nortriptyline, procainamide, quinidine, salicylic acid, sulfamethoxazole, tobramycin, trimethoprim, valproic add, vancomycin... 

Four patients taking tricyclic antidepressants (imipramine, clomipramine, dibenzepin) and one taking viloxazine relapsed into depression when they took co-trimoxazole (trimethoprim with sulfamethoxazole) for 2 to 9 days. The reasons are not known. Another patient treated for 5 years with alprazolam and imipramine for panic disorder and who had not had panic attacks for several months developed insomnia, anxiety and panic attacks within 6 days of starting to take co-trimoxazole. The panic... 

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