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Imidazolium hydroxide ring

A typical role for the histidine imidazole ring is shown below, in the enzyme mechanism for a general base-catalysed hydrolysis of an ester. The imidazole nitrogen acts as a base to remove a proton from water, generating hydroxide that attacks the carbonyl. Subsequently, the alkoxide leaving group is reprotonated by the imidazolium... [Pg.434]

See other pages where Imidazolium hydroxide ring is mentioned: [Pg.250]    [Pg.250]    [Pg.136]    [Pg.157]    [Pg.7]    [Pg.16]    [Pg.129]    [Pg.737]    [Pg.129]    [Pg.408]    [Pg.129]    [Pg.408]    [Pg.206]    [Pg.188]    [Pg.222]    [Pg.302]   


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Imidazolium

Imidazolium hydroxide

Imidazolium ring

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