Imidazole 4-hetaryl

Hybrid l-hetaryl-2-thienylperfluorocyclopentenes containing the thiazole 90 (04T6155) (Scheme 30), pyrrole 91 (07OL2139), imidazole 92 (09CEJ1577), or pyrazole 93 (06TL6473) rings were described. 

Ferner gelingt es durch Belichten von 4-Hetaryl-substituierten 3,4-Dihydro-pyrimidinen in Ace-ton 4(5)-Hetarylmethyl-imidazole in Ausbeuten um 50% zu erhalten438. 

Analogous imidazoderivatives under the action of CBT undergo hetarylation at the methyl group of the imidazole moiety (80KGS1424) (Scheme 53). 

SCHEME 12.10 Synthesis of 2-phenyl-4(5)-(2 -hetaryl)imidazoles 38 by Weidenhagen reaction. 

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