Imidacloprid selective toxicity

In contrast, the neonicotinoids are not protonated and therefore bind differently, resulting in greater activity on insects than manunals. It is this selective toxicity that has led to extensive use of the neonicotinoids and they represent about 20% of the global insecticide market [34]. Worldwide sales of neonicotinoid insecticides are estimated at 1 billion [35]. Imidacloprid and thiacloprid are examples of neonicotinoid insecticides. 

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