Hypothesis proving

Skell s hypothesis proved to be extremely useful in carbene chemistry even though it was frequently opposed. The principal significance of these rules is represented in the scheme below. The singlet reaction occurs in a concerted step, the cis-addition product being formed in a stereospeciiic manner. In the triplet addition, which is a two-step reaction, rotation is thought to be faster than intersystem crossing (spin inversion) and ring closure, i.e., which would... 

Beginning in 1956, E. M. Flanigen learned how to make X with silica/alumina ratios between 4.0 and 5.7. Now with a full range of ratios from 2.5 to 5.7, we were able to study systematically the variation in properties with alumina content. Breck s original hypothesis proved to be correct. The high silica forms were more stable to acid attack and to high temperatures in the presence of water vapor than the low silica forms [23]. 

Van Rooij and co-workers [126] used MALDI on an external ion source Fourier transform ion cyclotron resonance mass spectrometer (FT-ICR-MS) to analyse the block length distributions of triblock polymers of poly(oxypropylene) and poly(oxyethylene). For the first time, detailed and accurate molecular weight data were obtained on a complex sample using this methodology, which independently validated the data provided by the manufacturer. The experimentally verified random coupling hypothesis proved the validity of the methodology. 

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