Hyperalgesia clinical implications

Chu LF, Clark D, Angst MS. Molecular basis and clinical implications of opioid tolerance and opioid-induced hyperalgesia. In Sinatra RS, de Leon-Casasola OA, Ginsberg B, Viscusi ER, eds. Acute Pain Management. New York Cambridge University Press,... 

Figure 38.1. Clinical algorithm for differentiating worsening pain states despite continuation of opioid therapy. (Reprinted with permission from Mitra S. Opioid-induced hyperalgesia pathophysiology and clinical implications. J Opioid Manage 2008 4 123-130.)...

Mitra S. Opioid-induced hyperalgesia pathophysiology and clinical implications. / Opioid Manage 2008 4 123-130. 

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