Hymenocallis arenicola

Amisine (41) has been isolated from this plant.46 

This sponge, found in the Red Sea, produces a number of toxins, three of which have been isolated and identified as possessing a thiazolidinone ring that is connected to a fourteen-membered macrolide ring.47 Latrunculins A and B have been assigned structures (42) and (43), and latrunculin C is a stereoisomer of (42). 

An antibiotic, myxothiazole (44), has been obtained from this fungus.48 MeO OMe 

---

Although the alkaloids of the mesembrane type are structurally similar to certain alkaloids of the family Amaryllidaceae, they are generally found in the plants of the family Aizoaceae, but there have been several exceptions to this generalization. For example, amisine (580) has been isolated from Hymenocallis arenicola Northrop (57), and mesembrenol (581) has been isolated from Crinum oliganthum (41). The isolation of 580 and 581 represented the first instances in... 

Doepke and co-workers have isolated more new alkaloids from Hymenocallis arenicola. Havanine (1) is a new member of the crinine group the presence of two methoxyl groups and one attached to an sp3 carbon was indicated by the n.m.r. spectrum, and the structure of the alkaloid was proposed mainly on the basis of the mass spectrum.2 Structure (2) for caribine was assigned as a... 

Few isolations of mesembrine-type alkaloids have been reported. Two examples are the isolation of amisine (379) (from Hymenocallis arenicola) (183) and of mesembrenol (380) (from Crinum oliganthum) (184) from the Amaryllidaceae family. A third example is the isolation of mesembrenone (381), belonging to the mesembrine group, from the aerial parts of Narcissus palladulus (77) growing in Iberia. The structure was elucidated by spectroscopic and chemical methods (Fig. 22). 

A new isomer of galanthine, zaidine (5), has been isolated from Hymenocallis arenicola. The structure of zaidine was determined by mass spectrometry, but its stereochemistry is unknown. H. arenicola also contains lycorine, tazettine, galanthamine, and haemanthamine. 

---