26-Hydroxysteroids absolute configuration

Electronic circular dichroism for compounds without a chromophore To determine the absolute configuration of compounds without a chromophore in the accessible spectral region one or more proper groups can be derivatized to obtain an appropriate chromophoric system. The substitution of di-hydroxysteroids with two p-methoxybenzoates can be mentioned as an example. The substitution leads to an inherent dissymmetric chromophore for which the exciton chirality method can be applied. For chiral diols and amino alcohols another interesting possibility does exist. Complexing of these diols and amino alcohols with a transition metal... 

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