Hydroxyphosphines as Ligands

Aqueous-Phase Organometallic Catalysis, Second Edition 

Copyright 2004 WILEY-VCH Verlag GmbH Co. KGaA, Weinheim 

Simple hydroxyphosphines can be prepared conveniently by the ring-opening reaction of cyclic ethers with phosphides (Eq. 1) [4], 

Phosphine and hydroxy groups emerge simultaneously and therefore subsequent reaction with the air-sensitive hydroxyphosphine can be avoided. The structure of the cyclic ether determines in each case the distance separating functional groups in the product this means epoxides form 1,2-hydroxyphosphines, 1,3-prod-ucts can be produced by the employment of oxetanes [5], etc. Problems may be caused by the formation of regio- and stereoisomeric byproducts during the ringopening step by application of internal nonsymmetric cyclic ethers [6], 

As shown by Katti et al. the nucleophilic addition of PH3 or primary phosphines 

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Borner A (2004) Other concepts hydroxyphosphines as ligands. In COTnils B, Herrmann WA (eds) Aqueous-phase organometalhc catalysis, 2nd edn. Wiley-VCH, Weinheim, pp 187-193... 

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