2- Hydroxy-nitrogen heterocycles complexation reactions

A related approach to the synthesis of nitrogen heterocycles also proceeds via Pd -catalyzed alkene aminopalladation, but involves substrates bearing allyhc acetates or allylic hydroxy groups [21, 22]. In contrast to the oxidative amination reactions described above, these transformations are terminated by 3-elimination of the acetate or hydroxy group (rather than P-hydride elimination). This approach alleviates the need for added oxidants, but does require the use of slightly more complex substrates. Nonetheless, this method is quite useful, and has been applied to the synthesis of... 

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