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Hydroperoxides, iron -induced activation

AUomargaritarine (284) can inhibit the Hpid peroxydation process (POL) triggered by either iron ions or feri-butyl hydroperoxide in a rat model. It also exhibited a Fe " " chelating capacity and a weak radical scavenging activity.A small library of C15-aminated securinine derivatives was prepared and evaluated for their antioxidant potential. Only allomargaritarine (284), 5-methoxy allomargaritarine (285), and pyridine derivative 287 showed interesting POL inhibition activities in iron-induced models (Scheme 53). In constrast, securinine (1) did not influence the POL. [Pg.109]

See other pages where Hydroperoxides, iron -induced activation is mentioned: [Pg.45]    [Pg.275]    [Pg.1060]    [Pg.153]    [Pg.578]    [Pg.215]    [Pg.346]    [Pg.360]    [Pg.105]    [Pg.42]    [Pg.244]    [Pg.308]    [Pg.215]   
See also in sourсe #XX -- [ Pg.85 , Pg.86 , Pg.87 , Pg.88 , Pg.89 , Pg.90 , Pg.91 , Pg.92 , Pg.93 , Pg.94 , Pg.95 ]



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