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Hydrolytic degradation Explorer

Currently, application opportunities for poly()5-hydroxybutyrates) (PHB) - a member of the polyhydroxy alkanoate group - are being explored. Only very mild body reactions were detected with PHB implants during an implantation time of 12 months, there were no indications of chronic inflammation reactions. Enzymes accelerate hydrolytic degradation of PHB [954]. [Pg.881]

Owing to their pronounced hydrolytic instability, polyanhydrides have therefore been explored as degradable implant materials. Aliphatic polyanhydrides degrade within days whereas some aromatic polyanhydrides degrade over several years. Thus, aliphatic-aromatic copolymers, having intermediate rates of degradation, are usually employed. [Pg.129]

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See also in sourсe #XX -- [ Pg.193 ]

See also in sourсe #XX -- [ Pg.193 ]



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