Hydrolysis of carbonates and esters

As the first test reaction, the hydrolysis of carbonates and esters was selected according to the above criteria (Figure 18.2). Corresponding antibodies were indeed found. Typically, such antibodies catalyze reactions by a factor of 103-104 over back-... 

Figure 18.2 Hydrolysis of carbonates and esters by catalytic antibodies (Lerner, 1991).

Figure 8.12. Picture of transition states, antigen with transition state analogous to transition states for the hydrolysis of carbonates and esters and Diels—Alder reaction. Adapted from R.A. Lerner et...

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