Hydrodehalogenation of alkyl halides

For efficiency and reasons of economy THF is recommended. Representative dehalogenations in THF are shown in Table 1. Most alkyl halides are reduced at 25 C to alkanes, except for bicyclic halides, such as eA o-2-bromonorbomane. In most cases, the reaction exhibits the typical characteristics of an 5n2 substitution reaction in the reactivity order I > Br > Cl primary > secondary > tertiary. In all cases, no al-kene, or only traces of it, is formed as a side product as a result of elimination. This method provides a convenient synthetic procedure for hydrodehalogenation of alkyl halides. 

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See also in sourсe #XX -- [ , , ]

See also in sourсe #XX -- [ , , , ]

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