Hydroaminomethylation mechanism

This atom economic reaction, in which only water occurs as a by-product, is very attractive for forming various amines. Hydroaminomethylation includes three different mechanisms due to the three reactions involved. The mechanism of hydroaminomethylation is shown in Scheme 17. The first catalytic cycle is similar to hydroformylation, which is described above. 

Assuming that the first step in the catalytic cycle is photoactivation of the Rh complex, propose a possible mechanism for the transformation above. 9-9 The transformation on the next page is called hydroaminomethylation, first... 

Hydroaminomethylation can be considered to be a sequence of two catalytic processes linked by an uncatalyzed process, as summarized in Scheme 17.16. First, catalytic hydroformylation of an alkene occurs by the steps described in the previous section on hydroformylation. This process is then followed by an uncatalyzed condensation of the amine with the aldehyde. When this reaction is conducted with a secondary amine, an enamine results and when the reaction is conducted with a primary amine, an imine results. This condensation process is then followed by hydrogenation of the resulting enamine or imiiie by the mechanisms described in Chapter 15, the chapter on hydrogenation. 

Heavy-ends Heck mechanism heteroatom-directed hydroformylation B-hydride elimination hydroaminomethylation hydrocya nation hydrolysis phosphites... 

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