Hydroamination hydrosilylation, tandem

The above-mentioned iridium complex, C4, as well as [ lr[bis(l-methylimidazol-2-yl)methane (CO)2][BPh4] (C5), also appeared very efficient in a one-pot tandem hydroamination/hydrosilylation reaction of 4-pentyn-l-amine with HSiEts to form 2-methylpyrroline, and then subsequently l-(triethylsilyl)-2-methylpyrrohdine with an essentially quantitative yield (Equation 14.5) [54]. 

Synthesis of Chiral Amines via Tandem Hydroamination/Hydrosilylation... 

Equation 11.14. Titanium catalyzed tandem hydroamination/hydrosilylation of aminoalkynes [133]. 

P,N-Phosphine imine complexes of iridium (25) have also proved to be successful in intramolecular reactivity to give indole products, and intermolecular tandem catalytic routes have been developed to complete hydroamination/hydrosilylation sequences to realize secondary amine syntheses upon workup (Scheme 15.27) [188]. In this case, the Markovnikov products are obtained and enhanced catalyst efficiency is realized in the presence of weakly coordinating anions such as... 

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