3-Hydrazino-2 -quinoxalinone

Hydrazino-2(l//)-quinoxalinone gave 3-benzylidenehydrazino-2(l/7)-quinox-alinone (228) (PhCHO, EtOH, reflux, 5 h >95% ° or PhCHO, Me2NCHO,... [Pg.301]

Benzoyl-l-ethoxycarbonylethylidene)hydrazino]-2(l//)-quinoxalinone (284) gave 2-phenacyl- //-[ 1,2,4]triazino[4,3-a]quinoxaline-1,5(6/f)-dione (285)... [Pg.311]

Hydrazino-l-methyl-2(l//)-quinoxalinone 2-Hydrazino-3-methylthioquinoxaline 2-Hydrazino-3-pentylquinoxaline 2-Hydrazino-3-phenylquinoxaline 2-Hydrazino-3-piperidinoquinoxaline 2-Hydrazino-3-propylquinoxaline... [Pg.410]

Hydrazino-2(17/)-quinoxalinone 2-Hydrazino-3,6,7-trimethylquinoxaline 5-Hydroxyamino-7-methoxyquinoxaline 2-Hydroxyaminoquinoxaline... [Pg.410]

Quinoxaline-2,3-dione is converted into 2,3-dichloroquinoxaline by phosphoryl chloride142 or phosphorus pentachloride.143 2,3-Dibromo-quinoxaline is similarly obtained using phosphoryl bromide in dimethyl-aniline.144 Quinoxalin-2-one undergoes ring contraction to 2-methyl-benzimidazole (134) with hydrazine145 however, quinoxaline-2,3-dione gives 3-hydrazino-2-quinoxalinone.145 Quinoxalin-2-one yields a 3-p-dimethylaminophenyl derivative with 7V,N-dimethylaniline (in AcOH, with NH4N03), and a 3-(indol-3-yl) derivative with indole.146... [Pg.399]

DMQPH = 6,7-dimethoxy-l-methyl-2(177j-quinoxalinone-3-proprionylcarboxylic acid hydrazide, HCPI = 2-(4-hydrazinocarbonylphenyl)-4,5-diphenyli-midazole, DBPM = 7V-[4 (6 dimethylamino-2-benzofuranyl)phenyl]maleimide, DNS-H = dansyl hydrazine, DBD H = 4 (AA -dimethylaminosulphonyl) 7-hydrazino-2,l,3-benzoxadiazole, DETBA = l,3-diethyl-2-thiobarbituric acid, DCIA = 7-dimethylamino-3- 4-[(iodoacetyl)amino]phenyl -4-methylcou marin, m-CED = 1, 2-bjs(3-chlorophenyl)ethylenediamine. [Pg.413]

Treatment of the dihydroimidazo[l,2-a]quinoxaline 19 with sodium hydroxide solution results in opening of the five-membered ring and formation of the quinoxalinone 20. The 4-chloro derivative 21 is susceptible to nucleophilic attack, and displacement of the chlorine has been achieved with sodium methoxide, sodium alkoxides in benzene, and hydrazine. The 4-hydrazino derivative was not isolated but was treated with copper sulfate and sodium hydroxide to give the 4-unsubstituted compound. ... [Pg.656]

Hydrazino compounds can react with carboxy compounds in aqueous medium to form hydrazide. For the reaction to proceed under mild conditions, N-ethyl-N -(3-dimethylaminopropyl) carbodiimide (EDC) is required as a condensing reagent. Fatty acids are determined with 2-nitrophenylhydrazine hydrochloride (NPH) by LC-UV detection. The detection limits for long chain fatty acids are 2.5-5 pmol per injection. As FL derivatization reagents, 6,7-dimethoxy-l-memyl-2( lH)-quinoxalinone-3-propionyl carboxylic... [Pg.1792]

Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...