Hydantoins 1.3- dibromo-5,5-dimethylhydantoin

Trifluoromethyl-substituted aromatic compounds are obtained by reacting methyl arenecar-bodithioates with tetrabutylammonium dihydrogen trifluoride and l,3-dibromo-5.5-dimethyl-hydantoin. The use of /V-bromosuccinimide or A-iodosuccinimide instead of l,3-dibromo-5,5-dimethylhydantoin affords difluoro(methylsulfanyl)methyl-substitutcd aromatics.62... 

N-Bromosuccinimide and IV,IV-dibromo-5,5-dimethylhydantoin have also been used successfully, which makes possible recycling of succinimide or the hydantoin and utilizes all the bromine atoms. A mixture of sodium bromide—sodium bromate in aqueous acid has also been used commercially. 

Bromine fluoride can also be added by means of various reagents. The source of bromine is most often iV-bromoacetamide,171,172,198,251 iV-bromosuccinimide (NBS), 21 5,217.220.245-24-8. 254,696,698 i,3-dibromo-5,5-dimethylhydantoin (DBH).245,275,278 l-bromo-3,5,5-trimethyl-hydantoin(BTH),316 or bromine.108,197,217,227-229-261 The fluoride source is usually hydrogen fluoride,217,245,251,254 boron trifluoride,260 bromine trifluoride.227,261 xenon difluoride,108 tet-rabutylammonium dihydrogen trifluoride,694 tetrabutylphosphonium dihydrogen trifluo-... 

Dibromo-5,5-dimethylhydantoin Hydantoin, 1,3-dibromo-5,5-dimethyl- (8) 2.4-Imidazolidinedione, 1,3-dibromo-5,5-dimethyl- (9) (77-48-5)... 

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