Hyacinthacines family

Other synthetic approaches to hyacinthacine skeleton using the xylose-derived nitrone were reported. In 2010, the synthesis of (—)-hyacinthacine A3 66 (the enantiomer of the naturally occurring (+)-hyacinthacine A3) was described by Hu et al. [20]. This member of the hyacinthacines family includes a chiral center at the C-5 position of the B-ring (Scheme 12). 

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