Hughes indole synthesis

For reviews on the Fischer indole reaction, see Robinson, B. "The Fischer Indole Synthesis" John Wiley and Sons New York, 1982 Hughes, D. L. Org. Prep. Proced. Int 1993,25, 60 Gribble, G. W. Contemp. Org. Synth. 1994, 1. 145 and references cited therein. 

The Eischer indole synthesis , Robinson, B., John Wiley Sons, Ltd, Chichester, New York, 1982 Progress in the Fischer indole reaction , Hughes,... 

Hughes developed a polymer-bound phosphonium salt support for a solid phase Wittig-Madelung indole synthesis (Scheme 8) [21]. The method uses a commercially available polymer-bound triphenylphosphine 22. 

Nicolaou KC, Roecker AJ, Hughes R, van Summeren R, Pfefferkom JA, Winssingta- N (2003) Novel strategies for the solid phase synthesis of substimted indolines and indoles. Bioorg Med Chem 11 465-476... 

Baker-Venkataraman rearrangement 338 Balaban synthesis (pyrylium ion) 302 Bamberger-Hughes-Ingold rearrangement 350 Barton-Zard synthesis (pyrrole) 120 Batcho-Leimgruber synthesis (indole) 136 Baylis-Hillman reaction 452 Beirut reaction 254, 500 Bemthsen synthesis... 

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