HPLC-ED in Analytical Toxicology

Detector Type Minimum sensitivity (nmol ) Selectivity Applicability Ease of use/ interpretation Typical price in UK  

Electrochemical Single electrode 1 high moderate moderate 5,000 

The drugs and other compounds reviewed are largely those given International Nonproprietary Names. Information on the dose, pharmacokinetics, metabolism and pKa values for some of these compounds can be found in standard works such as those of Moffat et al., Baselt and O Neil et al  

Barisci and G.G. Wallace, Electrochemical detectors for liquid chromatography, Chim. Oggi., 1990, 9-13. 

Cardosi, Electrochemical detection in HPLC An overview, Chromatogr. 

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