How to Analyze the Dialysate

The perfusate after microdialysis sampling is often compatible with both subsequent liquid chromatography and capillary electrophoresis analysis. In an off-line separating system, the microdialysate fractions are first collected and then analyzed. Analysis of the microdialysate can also be performed online. For this, the microdialysis and the separating unit need to be coupled. [Pg.185]

By coupling microdialysis to capillary electrophoresis, much shorter sampling times can be used, since the separating step can be very fast. As mentioned in Chapter 6, injection volumes are in the nanoliter range. This allows not only short sampling times but also a low perfusate flow rate that vhll give better detection limits (Section 9.6.1). [Pg.185]

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