Homochiral dendrimer

Chow and coworkers 40,41 reported the synthesis and characterization of homochiral dendrimers through the first generation by using (2R, 3i )-tartaric acid as the chiral building block. The mode of preparation is based on three parts the three-directional core, 1,3,5-trihydroxybenzene (61), the chiral connector, l-0-tosyl-4-terf-butyl-phenoxy-2,3-O-isopropylidene-L-threitol (62), and a branching unit, l-benzyloxy-3,5-dihydroxyben-zene (63). 

Scheme 7.14. Construction of homochiral dendrimers effected using (2ft,3A1)-tartaric acid-based building blocks.

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