HIYAMA Aminoacrylate synthesis

The Hiyama aminoacrylate synthesis " is the synthesis of alkyl ester of 3-aminoacrylic acids or derivatives by aldol-type condensation of nitriles with ester in the presence of a base such as (i-Pr)2NH. 

The mechanism of the Hiyama aminoacrylate synthesis reaction is similar to the aldol condensation, as shown in Scheme 3.10. 

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See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ ]

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