Hirulog early reperfusion/occlusion

Wong CK, Gao W, Stewart RA et al. Hirulog Early Reperfusion Occlusion (HERO-2) Investigators. Risk stratification of patients with acute anterior myocardial infarction and right bundle-branch block importance of QRS duration and early ST-segment resolution after fibrinolytic therapy. Circulation 2006b 114(8) 783. 

The Hirulog Early Reperfusion or Occlusion (HERO) trial was conducted in patients with AMI to investigate the effects of bivalirudin in combination with SKand aspirin (Table 5) (66). Four hundred and twelve patients who presented with onset of ST elevation within 12 hours were randomized in a double-blind manner to one of three adjunctive anticoagulation regimens, UFH, low-dose or high-dose bivalirudin. The... 

Abbreviations AMI, acute myocardial infarction HERO, hirulog early reperfusion or occlusion SK, streptokinase TIMI, thrombolysis in myocardial infarction UFH, unfractionated heparin. 

The Hirulog and Early Reperfusion or Occlusion (HERO) -2 Trial Investigators. Thrombin-specific anticoagulation with bivalirudin versus heparin in patients receiving fibrinolytic therapy for acute myocardial infarction the HERO-2 randomised trial. Lancet 2001 3 58 1 855-1 863,... 

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