Himbosine

The yield of total alkaloid varied from a trace to about 0.5%. The maj or and commonest alkaloids in bark from both sources were himbacine and himandridine. Himbadine and himgaline, which are structurally related, were also major alkaloids in bark from North Queensland but were not found in material from New Guinea, except in one instance when a trace of himgaline was isolated. Himbosine was usually present in small amounts in all samples but all of the other alkaloids occurred irregularly and should be regarded as minor. Some of them have been isolated only once. 

Since himbosine was available in only relatively small amount and since its structure appeared likely to provide the key to the large ester group an X-ray crystallographic examination of the hydrobromide was undertaken by Lovell (15). The structure determined by him is represented by XXVII, in which relative stereochemistry only is implied. 

Himbacine, himandridine, himbadine, himgaline, himbosine, himandrine, himgravine, himandreline, himbeline, himandravine, himgrine, alkaloid G.B. 13... 

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