Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

High-content toxicity screening

Persson, M. et al., 2014. High-content analysis/screening for predictive toxicology application to hepatotoxicity and geno-toxicity. Basic Clinical Pharmacology Toxicology, 115(1), pp. 18-23. [Pg.91]

Abraham, V.C., Towne, D.L., Waring, J.F., Warrior, U. and Burns, D.J. (2008) Application of a high-content multiparameter cytotoxidty assay to prioritize compounds based on toxicity potential in humans. Journal of Biomolecular Screening, 13, 527-537. [Pg.343]

O Brien, P.J. (2008) Chapter 13 High content analysis of sublethal cytotoxicity in human HepG2 hepatocytes for assessing potential and mechanism for chemical and drug-induced human toxicity, in High Content Screening Science, Techniques and Applications (ed. S.A. Haney), John Wiley Sons, Hoboken, NJ,... [Pg.343]

High-content screening (HCS) has been nsed for early cytotoxicity measurement since 2006 and provides great optimism (Persson et al., 2014). This method has been optimized for stem cell-derived models for the prediction of other organ toxicity. [Pg.90]

TABLE 8.1 Comparison of Outcomes between High Content Screening (HCS) Using HepG2 (Johnson Johnson), Human Hepatocytes (Pfizer), and Zebrafish Phenotypic Hepatotoxicity Screening (Evotec) against FDA Liver Toxicity Knowledge Base (LTKB) DILI Classification... [Pg.113]

O Brien PJ (2014) High-content analysis in toxicology screening substances for human toxicity potential, elucidating subcellular mechanisms and in vivo use as translational safety biomarkers. Basic Clin Pharmacol Toxicol 115, 4-17. [Pg.126]

See other pages where High-content toxicity screening is mentioned: [Pg.16]    [Pg.59]    [Pg.325]    [Pg.256]    [Pg.190]    [Pg.322]    [Pg.363]    [Pg.377]    [Pg.597]    [Pg.604]    [Pg.379]    [Pg.326]    [Pg.340]    [Pg.46]    [Pg.151]    [Pg.65]    [Pg.180]    [Pg.646]    [Pg.147]    [Pg.143]    [Pg.258]    [Pg.471]    [Pg.21]    [Pg.425]    [Pg.70]    [Pg.90]    [Pg.254]    [Pg.114]    [Pg.645]    [Pg.819]    [Pg.405]   
See also in sourсe #XX -- [ Pg.2 , Pg.626 ]

See also in sourсe #XX -- [ Pg.626 ]



SEARCH



High content

High content screening

High screen

High screening

High-content screen

Highly toxic

Toxicity high-content

© 2024 chempedia.info