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High-affinity radiolabeled ligand

A little over 10 years ago radiolabeled epibatidine (Houghtling et al. 1995) was introduced as a new ligand with extraordinarily high affinity for o4p2 nAChRs. Early reports suggested that [ H]-epibatidine binds to oc4p2-type receptors only, but this assertion was quickly questioned when it was noted that epibatidine binding exceeds... [Pg.95]

First, radiolabeled ligands are bound to receptor material in as specific a manner as possible ligands of high affinity are required with dissociation... [Pg.446]


See other pages where High-affinity radiolabeled ligand is mentioned: [Pg.374]    [Pg.374]    [Pg.177]    [Pg.225]    [Pg.342]    [Pg.509]    [Pg.374]    [Pg.375]    [Pg.54]    [Pg.946]    [Pg.217]    [Pg.129]    [Pg.272]    [Pg.277]    [Pg.279]    [Pg.29]    [Pg.261]    [Pg.263]    [Pg.264]    [Pg.207]    [Pg.372]    [Pg.128]    [Pg.129]    [Pg.131]    [Pg.133]    [Pg.172]    [Pg.29]    [Pg.219]    [Pg.41]    [Pg.207]    [Pg.113]    [Pg.20]    [Pg.145]    [Pg.369]    [Pg.162]    [Pg.5460]    [Pg.5484]    [Pg.1576]    [Pg.3115]    [Pg.3116]    [Pg.3124]    [Pg.366]    [Pg.199]    [Pg.367]    [Pg.362]    [Pg.406]    [Pg.247]    [Pg.108]    [Pg.913]   
See also in sourсe #XX -- [ Pg.374 ]




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Affinity ligands

High-affinity

Radiolabeling

Radiolabeling/radiolabeled

Radiolabelling

Radiolabels

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