Hexahydro-3- pyrrolo pyrazine-1,4-dione

The pyrolysis of human hair [15] showed that diketopiperazine formation could provide information on the structure of proteins. This study utilized a Py-GC/MS/MS approach, assigning structures to the compounds generating different chromatographic peaks using the MS/MS capability with both El and Cl ionization techniques. Besides compounds of the type hexahydro-3-(2-methylpropyl)-pyrrolo[1,2-a]pyrazine (1,4-diazabicyclo[4,3,0]nonane-3-methylpropyl-2,5-dione, see Figure 3.5.6d), a second series of compounds with the same mass were noticed. The daughter ions of the two series of compounds were different, showing that pyrolysis of proteins does have in fact... 

Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-methyl-, (ZR-trans)- 3553 ... 

Hexahydro-3-(l -methylpropyl)pyrrolo[l, 2-n]pyrazine-l,4-dione, H-60052 Spiro[5.5]undecane-3,9-dione Dioxime, in S-70068... 

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