Heuristics-aided quantum chemistry

The heuristics-aided quantum chemistry (HAQC) methodology of Rappoport et al. (2014) shows many similarities to those previously mentioned, and it has been used for the generation of detailed reaction mechanisms of organic chemistry transformations. 

Rappoport, D., Galvin, C.J., Zubarev, D.Y., Aspuru-Guzik, A. Complex chemical reaction networks fiom heuristics-aided quantum chemistry. J. Chem. Theory Comput. 10, 897-907 (2014)... 

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