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Heteroatomic nucleophiles intermolecular additions

The addition of heteroatom nucleophiles to Q , -unsaturated carbonyl compounds has also been promoted using TBDMS triflate. An intermolecular aza-double Michael reaction has been developed as a route to functionalized piperidin-2-ones (eq 27). Due to its relative ease of handling, TBDMS triflate was generally preferred to TMSI-HMDS as an additive in such reactions. [Pg.130]


See other pages where Heteroatomic nucleophiles intermolecular additions is mentioned: [Pg.3]    [Pg.791]    [Pg.48]    [Pg.360]    [Pg.142]    [Pg.121]    [Pg.142]    [Pg.142]    [Pg.188]    [Pg.421]    [Pg.4]    [Pg.205]    [Pg.192]    [Pg.1]   


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