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Hetero lysis

Figure 1-3. The cytochrome P450cain catalytic cycle. Upon binding, the substrate displaces water, converting the heme from six-coordinate, low-spin (1) to five-coordinate, liigh-spin (2). Subsequent reduction by putd produces a ferrous heme, which binds dioxygen (3). Reduction of 3 produces a ferrous, peroxide-bound heme (4), which rapidly protonates (5). In the prevalent model, the peroxide then undergoes hetero lysis to produce water and a ferry 1 [Fe(IV)=O] + species (compound I, 6), which oxidizes the substrate. See refs. 87-89. Figure 1-3. The cytochrome P450cain catalytic cycle. Upon binding, the substrate displaces water, converting the heme from six-coordinate, low-spin (1) to five-coordinate, liigh-spin (2). Subsequent reduction by putd produces a ferrous heme, which binds dioxygen (3). Reduction of 3 produces a ferrous, peroxide-bound heme (4), which rapidly protonates (5). In the prevalent model, the peroxide then undergoes hetero lysis to produce water and a ferry 1 [Fe(IV)=O] + species (compound I, 6), which oxidizes the substrate. See refs. 87-89.
These words are taken from the Greek homo and hetero, the same and different and lysis, a loosing. To a chemist lysis means cleavage as in, for example, hydro-lysis, cleavage by water. )... [Pg.21]


See other pages where Hetero lysis is mentioned: [Pg.75]    [Pg.346]    [Pg.597]    [Pg.134]    [Pg.263]    [Pg.21]    [Pg.75]    [Pg.346]    [Pg.597]    [Pg.134]    [Pg.263]    [Pg.21]    [Pg.387]    [Pg.100]   
See also in sourсe #XX -- [ Pg.69 , Pg.71 , Pg.187 ]




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Lysis

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