Hetero Diels-Alderreaction

The catalyzed generation of a chiral enolate equivalent, formed from an enal and a triazoHum-derived chiral V-heterocyclic car-bene, can undergo a hetero-Diels-Alderreaction withenones with excellent enantioselectivity and diastereoselectivity (eq 14, left side). Alternatively, the authors have previously shown that stronger bases, such as DBU, instead result in a homoenolate... 

M. Radi, V. Bernardo, B. Bechi, D. Castagnolo, M. Pagano, M. Botta, Tetrahedron Lett. 2009,50,6572-6575. Microwave-assisted organocatalytic multicomponent Knoevenagel/hetero Diels-Alderreaction for the synthesis of 2,3-dihydropyran[2,3-c]pyrazoles. 

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See also in sourсe #XX -- [ , , , , , , , , , ]

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