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Hepatotoxicity associated with specific solvents

David K. Bonauto, C. Andrew Brodkin, William O. Robertson [Pg.1396]


The toxic effects of organic solvent compounds on the liver are dependent on the intensity and duration of exposure, route of exposure, the intrinsic toxicity of the specific compound, as well as individual susceptibility factors. There are a number of pathologic manifestations of solvent induced hepatotoxicity, including inflammation, fat accumulation in the liver (steatosis), hepatocellular necrosis and carcinogenesis. Functional disturbances in liver physiology have also been associated with solvent exposure. [Pg.1393]


See other pages where Hepatotoxicity associated with specific solvents is mentioned: [Pg.1395]    [Pg.1395]    [Pg.919]    [Pg.1395]    [Pg.1395]    [Pg.919]    [Pg.1395]    [Pg.1395]    [Pg.1395]    [Pg.1395]    [Pg.919]    [Pg.919]   


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Associated solvents

Hepatotoxicity

Hepatotoxity

Solvents association

Solvents specification

Specific solvents

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