Hemolysis elevated liver enzymes low platelets

HELLP, Hemolysis, elevated liver enzymes, low platelets. 

Fig. 8 Patient with hypertensive encephalopathy secondary to eclampsia with the HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome, (a) A T2-weighted MRl showing the extensive cerebral edema in the posterior white matter regions with less involvement of the gray matter, (b) Diffusion-weighted images with only one small area of involvement. The lack of DWl changes is consistent with this being a vasogenic type of edema, and the patient had a good recovery without residual...

Two Japanese primigravidae, aged 25 and 28 years, developed the HELLP syndrome, a severe variant of preeclampsia in which there is Hemolysis, Elevated Liver enzymes, and a Low Platelet count (4). They were given parenteral hyoscine butylbromide for abdominal pain and had seizures 60-90 minutes later. One died from intracerebral hemorrhage some days later and the other survived after a cesarean section soon afterward. The authors speculated that anticholinergic drugs may enhance sympathetic nervous system activity, and in particular vasoconstriction, and should be avoided in pre-eclampsia. It is not clear how widespread their use is... 

Sabai BM. The HELLP syndrome (hemolysis, elevated liver enzymes, and low platelets) much ado about nothing Am J Obstet Gynecol 1990 162 311-6. 

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