Hematin modified

Only the subunits with intact prosthetic groups are modified (IIS) and the inhibited product contains approximately one equivalent of AT per hematin bound at His-74 (112, US) most probably as in formula (III) (113a) ... 

Fig. 8. Preparation and hydrogen bond formation of poly(NIPAM)-co-imidazole microgel particles, (a) Preparation of the microgel particles (b) hydrogen formation the modified microgel interacts with an aqueous solution of hematin to form a hydrogen bonded species.

Pegylated hematin was developed as an effective biomimetic catalyst for polymerization of various anihnes [56]. PEG modified hematin, a biomimetic catalyst, was used in the synthesis of PEDOT and PPYR at the presence of SPS template [57]. The polymerization was carried out in an aqueous solution at pH 1.0. The polymers were electrochemically active. Conductivity was measured as 10 S/cm for PEDOT and 10 S/cm for PPYR. The conductivity was substantially improved by the copolymerization of PEDOT and PPYR and was found to be in the range of O.l-l.O S/cm. 

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