Hedyotis auricularia

Purushothaman, K.K Sarada, A. Structure of auricularine, a bis-indole alkaloid from Hedyotis auricularia. Phytochemistry. 1981,20,351-352. 

Ratnagiriswaran, A.N Venkatachalam, K. Auricularine-a new alkaloid from the roots and stems of Hedyotis auricularia. Journal India Chem. Soc. 1942, 19, 389. 

A number of alkaloids have been isolated from only three Hedyotis species, which are H. auricularia, H. chrysotricha and H. capitellata. The bis-indole alkaloids, hedyotine and auricularine were both isolated from the roots of H. auricularia [6,24]. However, the molecular formula and the structure of auricularine was revised later [19]. Auricularine (1) belongs to a novel group of bis-indole alkaloids, borreverine (lb) and isoborreverine [25] whose structures were established by X-ray crystallography and HRMS. Spectroscopic experiments found auricularine to differ from borreverine in its molecular formula by the presence of only a... 

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