Heart flumazenil

Midazolam and diazepam decrease arterial pressure without a change ia heart rate. Like thiopeatoae, midazolam is a respiratory depressant. Advantages of midazolam are its amnestic effect, coupled with less postoperative depression (102). A reversal agent for the benzodiazepiaes has also become available. Flumazenil [78755-81-4] C25H24FN2O2, (5) displaces the beazodiazepiaes from their receptor but has Httie demoastrable activity of its owa (103,104). 

Complete heart block occurred when flumazenil was given to a woman who had taken an overdose of paracetamol and temazepam [lOS J. 

Herd B, Clarke F. Complete heart block after flumazenil. Hum Exp Toxicol 1991 10(4) 289. 

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