Hamiltonian tiling model

In water solution, as shown by AMSOL calculations, the conformational preferences of the studied amides show up. Gibbs free energies of hydratation calculated witii tile SMS.4 model and PM3 hamiltonian for stmctures optimized at the RHF/6-3 1G level indicated tiiat those most favored by hydratation are the T- and G-conformers for tiie diamide and N,N,N ,N -tetramethyldiamide of (R, R)-tartaric acid, respectively. 

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