Halides homologation, phenylthiomethyllithium

The two schemes showing homologation of halides through alkylation of phenylthiomethyllithium as the key step for carbon-carbon bond formation illustrate the potential of this reagent [303],... 

Phenylthiomethyllithium (2a) was used for the homologation of primary halides in a two-step sequence first halogen displacement by reagent (2a) or the organocuprate derivative (in the case of allylic compound) and then replacement of the phenylthio group by iodo by heating the sulfide with a large excess of methyl iodide in 1 M sodium iodide solution in DMF (Scheme 16). 

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See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ , ]

See also in sourсe #XX -- [ ]

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