Guanosine 5 -phosphate, structure

A structure determination of CdL(H20)5 3H20 (L = guanosine-5 -phosphate) reveals a cadmium ion octahedrally coordinated by live water molecules and the N-7 of the purine ring system (Cd—N = 2.37 A Cd—O = 2.24-2.34 A).568 Similarly, a structure determination of CdL2(H20)4 (L = 8-azahypoxanthinato) reveals octahedral cadmium bonded to N-7 of the purine anions and to four water molecules.569 Theophylline (83) is frequently used as a substitute for guanine (84) in model systems, and the complexes [CdI (RNH2)2(H20)2] (L = 83) have been described.570... 

Draw the complete structure of guanosine 5 -phosphate, one of the four ribonucleotides. 

Campbell JM, von Sonntag C, Schulte-Frohlinde D (1974) Photolysis of 5-bromouracil and some related compounds in solution. Z Naturforsch 29b 750-757 Candeias LP, Steenken S (1989) Structure and acid-base properties of one-electron-oxidized deoxy-guanosine, guanosine, and 1-methylguanosine. J Am Chem Soc 111 1094-1099 Candeias LP, Steenken S (1992a) Electron adducts of adenine nucleosides and nucleotides in aqueous solution protonation at two carbon sites (C2 and C8) and intra- and intermolecular catalysis by phosphate. J Phys Chem 96 937-944... 

If we attach the nitrogenous bases to a ribose, we have the RNA nucleosides. The four RNA nucleoside bases are adenosine, uridine, cytidine, and guanosine. Usually, these nitrogenous bases are represented as A, U, C, and G, respectively. Figure 12.69 gives the names and structures of these compounds. Addition of a phosphate group to carbon 5 of the ribose sugar affords the RNA nucleotide bases. 

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