GSTM1 genotype

Howells RE, Redman CW, Dhar KK et al. Association of glutathione S-transferase GSTM1 and GSTT1 null genotypes... 

Gabbani G, Pavanello S, Nardini B, et al. 1999. Influence of metabolic genotype GSTM1 on levels of urinary mutagens in patients treated topically with coal tar. Mutat Res 440 27-33. 

GSTM1 null genotype, and risk of bladder cancer results from the... 

Polymorphisms Approximately 50% of Caucasians and E. Asians do not have a gene for GSTMl. This is termed the null allele GSTM1 0). In some Polynesian and Micronesian populations, the allele frequency is very high (>90%), whereas in Africans, the null allele occurs much less frequently ( 20-25% homozygous for the null genotype) (Table 3.12). 

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