Grunwald theory, enthalpy-entropy

Recently, experimental confirmation of the Grunwald theory was achieved by comparison of the quality of differential enthalpy-entropy compensation plots for the exchange equilibrium between (R)- and (S)-enantiomers of chiral guests in ff CyD cavities (Eq. (9)) [82], and the exchange equilibrium between native fi-CyXi and 6-ammonio-6-deoxy-jg-CyD (am- 8-CyD) for chiral and achiral guests (Eq. (10)) [119] ... 

The linear dependence of the activation energy on the logarithm of the frequency factor (both quantities calculated by the Arrhenius equation) is usually classified also as a linear free-energy relationship (cf. Wells, 2 Lefiler and Grunwald, 3). In terms of the transition state theory, this is a relationship between activation entropy and activation enthalpy ... 

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