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Growth hormone clinical significance

Several clinical studies have shown buspirone (14a) to have anxiolytic efficacy equivalent to that of DZ with significantly less sedation. ° Rats trained to discriminate oxazepam or pentobarbital from vehicle did not generalize to buspirone. At doses above those which are anxiolytically relevant in man, the drug caused a dose-related elevation of plasma prolactin in male subjects, and like the BZ s also increased growth hormone levels. Buspirone elicits a dose-dependent rise in rat striatal dopamine (DA) metabolite levels and may do so by selective antagonism of presynaptic DA autoreceptors with minimal postsynaptic effects. Its catalepsy-reversal effects may occur... [Pg.15]

See other pages where Growth hormone clinical significance is mentioned: [Pg.227]    [Pg.228]    [Pg.191]    [Pg.513]    [Pg.607]    [Pg.477]    [Pg.348]    [Pg.37]    [Pg.319]    [Pg.105]    [Pg.54]    [Pg.63]    [Pg.1802]    [Pg.3166]    [Pg.251]    [Pg.469]    [Pg.1411]    [Pg.1413]    [Pg.1415]    [Pg.2319]    [Pg.2651]    [Pg.105]    [Pg.211]    [Pg.419]    [Pg.479]    [Pg.102]    [Pg.258]    [Pg.258]    [Pg.177]    [Pg.450]    [Pg.197]    [Pg.680]    [Pg.176]    [Pg.20]    [Pg.57]    [Pg.66]    [Pg.183]    [Pg.151]    [Pg.208]    [Pg.24]    [Pg.264]    [Pg.66]    [Pg.394]    [Pg.1450]    [Pg.2340]    [Pg.2360]    [Pg.2367]    [Pg.177]    [Pg.422]    [Pg.338]   
See also in sourсe #XX -- [ Pg.1971 , Pg.1972 , Pg.1972 , Pg.1973 ]



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Clinical significance

Growth hormones

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