Glycosidic torsion

In Fig. 3 all conformers are plotted within 3 kcal/mol above, the global minimum found by CICADA for each of the glycosidic torsions, superimposed on the corresponding disaccharide relaxed map. Fig. 4 clearly indicates that most of the local minima present in the corresponding disaccharide fragments are also explored along the PES of the pentasaccharide by CICADA... 

P2j Z = 2 D = 1.17 R = 0.080 for 3,888 intensities. This is aconfigu-rational analysis of the macrolide antibiotic 23672RP from Streptomyces chryeus. All three sugar residues are pyranoid the conformation of the a-ketose is CX, with Q = 56 pm, 0 = 9° that of the / -D-mycinose (6-deoxy-2,3-di-0-methyl-D-allose) is 4Clt with Q = 59 pm, 0 = 6° and that of the / -L-mycarose (2,6-dideoxy-3-C-methyl-L-riho-hexose) is 1C4, with Q = 53 pm, 0= 177°. The O-5-C-l-O-l-C glycosidic torsion-angles are —71, —87, —83°. The atomic coordinates reported in the paper refer to the opposite enantiomer. 

Figure 1. Map of the minimized energy of the dimer Ag-Ig as function of the glycosidic torsion angles, with IdoA ring in form. Energy levels differ by. 5 kcal mol . ...

---