Glycosides hydrangea

N.A. Hydrangea arborescens L. Flavonoids, cyanogenic glycoside, saponins, hydrangein, tannin.99100 Treat kidney and bladder stones. 

The dihydroisocoumarin, 3i -phyllodulcin (3, obtained from the leaves of Hydrangea macrophylla var. thunbergii via enzymatic hydrolysis), was mentioned earlier in the chapter as having commercial use. Recently, it has been demonstrated that this sweet substance occurs naturally in unprocessed leaves of its plant of origin as a 5 1 enantiomer with the previously undescribed compound, 3S -phyllodulcin [111]. Also reported in this study were the novel 3R- and SS-phyllodulcin 3 -O-glycosides, although the presence or absence of a sweet taste in these three new phyllodulcin analogs was not disclosed [111]. 

The flower and leaf of hydrangea are reported to have caused toxic symptoms in humans. This is assumed to be due to the cyanogenic glycoside hydrangin, which is also... 

Chang F-R, Lee Y-H, Yang Y-L, Hsieh P-W, Khalil AT. Chen C-Y, Wu Y-C (2003) Secoiridoid glycoside and alkaloid constituents of Hydrangea chinensis. J Nat Prod 66 1245-1248... 

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